Article ID Journal Published Year Pages File Type
5508109 Biochimica et Biophysica Acta (BBA) - General Subjects 2017 38 Pages PDF
Abstract
Both BCRP and MRP1 were localized in mitochondria and participated to the reduction of mitochondrial accumulation of DOX in MCF-7doxR. This process was partly dependent of mitochondrial ATP synthesis. General Significance. The present study provides novel insights in the involvement of mitochondria in the underlying mechanisms of DOX-resistance in breast cancer cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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