Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Article ID	Journal	Published Year	Pages	File Type
5508119	Biochimica et Biophysica Acta (BBA) - General Subjects	2017	47 Pages	PDF

Keywords

EMEM Nrf2 NADPH GSH HRP HUVECS CFP DTNB HBSS PFA IκB HEK293 HIF TFA IL-8 BTB GCLC DMOG tert-butylhydroquinone EBM EcGS TFP TrxR1 4-2-hydroxyethyl-1-piperazineethanesulfonic acid Kelch like ECH associated protein 1 NF-κB PBS TNFα IL-6 FBS TBHQ HEPES 5,5′-dithiobis(2-nitrobenzoic acid)BSA keap1 cDNA Complementary DNA ROS Hydrogen peroxide bovine serum albumin EDTA Trifluoroacetic acid ethylenedinitrilotetraacetic acid Interleukin-8 interleukin-6 cardiovascular disease Thioredoxin reductase 1 tumor necrosis factor α Eagle's minimum essential medium minimal essential medium Endothelial function CVD Adaptation fetal bovine serum Human umbilical vein endothelial cells human embryonic kidney cells Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)Hypoxia Inducible Factor nuclear factor (erythroid-derived 2)-like 2 nuclear factor kappa-light-chain-enhancer of activated B cells Phosphate buffered saline Flavonoids MEM Hank's balanced salt solution endothelial basal medium Rutin endothelial cell growth supplement Nitric oxide H2O2 paraformaldehyde horse radish peroxidase cyan fluorescent protein reduced glutathione Glutamate cysteine ligase catalytic subunit Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Authors

Mireille M.J.P.E. Sthijns, Paul M. Schiffers, Ger M. Janssen, Kristien J.A. Lemmens, Bart Ides, Philippe Vangrieken, Freek G. Bouwman, Edwin C. Mariman, Irina Pader, Elias S.J. Arnér, Katarina Johansson, Aalt Bast, Guido R.M.M. Haenen,