Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5508163 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2016 | 31 Pages |
Abstract
The heuristic model is more intuitive than biophysically detailed models. It can serve as an important tool for interdisciplinary communication and even for psychiatric education of patients and relatives. This article is part of a Special Issue entitled “System Genetics” Guest Editor: Dr. Yudong Cai and Dr. Tao Huang.
Keywords
(NE)(LC)(Glu)(PCP)(DA)(ACh)(5-HT)(GABA)(VTA)(PFC)5,7-dihydroxytryptamineAcetylcholineSchizophreniagamma-aminobutyric acidsubstantia nigra pars compactaDopamineSystems biologySerotoninMobilePhencyclidineprefrontal cortexmedial prefrontal cortexdorsolateral prefrontal cortexlocus coeruleusInteraction matrixMesoscopic modelOrdinary differential equationsventral tegmental areanorepinephrinedorsal raphe nucleuslaterodorsal tegmental nucleusSubthalamic nucleusNeurotransmitterglutamate
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Authors
Zhen Qi, Gina P. Yu, Felix Tretter, Oliver Pogarell, Anthony A. Grace, Eberhard O. Voit,