| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5509028 | Biochimie | 2017 | 31 Pages |
Abstract
These results suggest that the protein adjustments observed in lipid raft/caveolin-1 microdomains could be visualized as a process required to protect the cells against NO overproduction and aberrant calpain activation. Alterations in eNOS, calpain-1 and HSP90 levels have been observed in aorta of Zucker Diabetic Rats (ZDR). The loss of HSP90 occurring in these animals indicates an aberrant activation of calpain and thereby the transition from a physiological to a pathological cell condition.
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Authors
Antonino Martines, Roberto Stifanese, Emanuela L. Faelli, Luisa Perasso, Ilaria Melloni, Piero Ruggeri, Monica Averna,