Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells

Article ID	Journal	Published Year	Pages	File Type
5509331	Cellular Signalling	2017	11 Pages	PDF

Keywords

UPR PKM1 protein kinase R-like ER kinase T2D FACS IRE1α inositol-requiring enzyme 1α ER stress Diabetes Terminal deoxynucleotidyl transferase dUTP nick end labeling TUNEL Apoptosis fluorescence-activated cell sorting Type 2 diabetes mellitus Pancreatic β cell endoplasmic reticulum Unfolded protein response PERK

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells

Authors

Yuta Horiuchi, Daiki Nakatsu, Fumi Kano, Masayuki Murata,