Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5509736 | Clinica Chimica Acta | 2017 | 7 Pages |
Abstract
This study shows for the first-time in humans that circulating miR-30c is significantly, positively correlated with total- and LDL-cholesterol implicating regulatory functions in lipid homeostasis. We show miR-30c is transported in both exosomes and on HDL3 and pravastatin therapy significantly increased circulating miR-30c expression adding to the pleiotropic dimensions of statins.
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Authors
Ravinder Sodi, Jarlath Eastwood, Muriel Caslake, Chris J Packard, Laura Denby,