| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5509849 | Clinica Chimica Acta | 2016 | 47 Pages |
Abstract
The genetic, pharmacological, physiological, and pathological aspects related to ADAMTS13/VWF have been extensively investigated. Here, we provide an update on recent findings of the relationship between ADAMTS13 and hematological/cardiovascular disorders, including thrombotic thrombocytopenic purpura, arterial thrombosis, thrombotic microangiopathy, myocardial infarction, ischemic stroke, heart failure, and hypertension.
Keywords
ST-segment elevation MITSP1TTPCCHDMMPSTEMIADAMTS13ECMDICTMAAmII/RROSMyocardial infarctionDIC, Disseminated intravascular coagulationischemia/reperfusioncardiovascular diseaseCyanotic congenital heart diseaseThrombotic thrombocytopenic purpuraTMA, Thrombotic microangiopathyArterial thrombosisthrombospondin type 1 repeatCubCVDEndothelial cellsAcute myocardial infarctionIschemic strokeAtrial fibrillationExtracellular matrixmatrix metalloproteinaseknockoutSingle nucleotide polymorphismSNPReactive oxygen species
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Authors
Omer Akyol, Sumeyya Akyol, Chu-Huang Chen,