Analysis of amino acids in human blood using UHPLC-MS/MS: Potential interferences of storage time and vacutainer tube in pre-analytical procedure

Article ID	Journal	Published Year	Pages	File Type
5509970	Clinical Biochemistry	2016	7 Pages	PDF

Abstract

Storage time and vacutainer tube were important variables for amino acid analysis. They should draw researchers' attention and then be controlled in good laboratory practice to reduce pre-analytical errors.

Keywords

THR PHE ALA MRM ISR KIM-1 sDMA ALB GLN HMDB NGAL CLSI Trp TBIL LEU DBil ESI Cys ALT GGT PBS A/G γ-glutamyltransferase Arginine AST alanine Alanine aminotransferase Albumin albumin/globulin ALP Alkaline phosphatase amino acid Arg Uric acid Hippuric acid MANOVA Oxo isoleucine Ile incurred sample reanalysis SER Direct bilirubin multivariate analysis of variance threonine aspartate transaminase Tryptophan Tyr Tyrosine KYN BUN HIS symmetric dimethylarginine storage time val Serine Cysteine Pre-analytical phase Phosphate buffered saline Phenylalanine Leucine Lysine LYS neutrophil gelatinase-associated lipocalin Methionine MET Clinical and Laboratory Standards Institute Kidney injury molecule-1 multiple reaction monitoring blood urea nitrogen histidine Valine human metabolome database serum creatinine glob total bilirubin total protein kynurenine Glu Globulin glutamine Glucose Gly Glycine electrospray ionization SCR

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Analysis of amino acids in human blood using UHPLC-MS/MS: Potential interferences of storage time and vacutainer tube in pre-analytical procedure

Authors

Tianyi Xia, Shouhong Gao, Chang Shu, Yan Wen, Yunlei Yun, Xia Tao, Wansheng Chen, Feng Zhang,