| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5510077 | Clinical Biochemistry | 2016 | 8 Pages |
Abstract
Serological biomarkers of collagen remodeling were elevated in subjects with COPD as compared with healthy individuals. Biomarker levels were significantly correlated with measures of dyspnea, indicating a relationship with degree of symptoms, while only C6M showed a weak but significant association with lung function. Biomarker levels were not related to GOLD grades, which was in line with previous studies indicating that ECM remodeling may be related to disease activity rather than severity.
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Authors
Jannie M.B. Sand, Gerd Martinez, Anne-Kirsten Midjord, Morten A. Karsdal, Diana J. Leeming, Peter Lange,