| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5510127 | Clinical Biochemistry | 2017 | 5 Pages |
Abstract
Marked discrepancies in thyroid hormone measurement were noted between reference LC-MSMS and a common immunoassay platform. It is hypothesized that T4 binding to low affinity albumin is displaced by several drugs, raising concentrations of FT4 by LC-MSMS compared to immunoassay, and that the immunoassay values are falsely decreased due to low binding proteins in our patient population.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Kerry J. Welsh, Brian R. Stolze, Xiaolin Yu, Trisha R. Podsiadlo, Lisa S. Kim, Steven J. Soldin,