Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5510911 | DNA Repair | 2017 | 39 Pages |
Abstract
Overall, our results indicate that tRNA genes are highly susceptible to ssDNA-specific DNA damaging agents. However, increased DNA repair efficacy in tRNA genes can prevent their hypermutation and maintain both genome and proteome homeostasis.
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Authors
Natalie Saini, Steven A. Roberts, Joan F. Sterling, Ewa P. Malc, Piotr A. Mieczkowski, Dmitry A. Gordenin,