Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5511887 | International Journal of Biological Macromolecules | 2017 | 19 Pages |
Abstract
We changed the situation that chitosan was only dissolved in diluted acid through mild physical treatment. In viewing of the usual methods to modify chitosan are chemical ones, we established the approach by using a water-soluble chitosan derivative as the model polymer. Its water-solubility was modulated via changing the concentration of solution and varying the precipitants. Such a physical method was adopted to treat chitiosan. One gram chitosan was dissolved in a mixture of 100Â mL 10% acetic acid and 50Â mL methanol, and then precipitated from a precipitant consisted of 10Â mL ethanol and 90Â mL acetate ester. The treated chitosan became soluble in acid-free water completely, and its solubility was 8.02Â mg/mL.
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Authors
Yinghao Fu, Congming Xiao,