| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5512838 | The Journal of Nutritional Biochemistry | 2017 | 27 Pages |
Abstract
Dietary lipids influence the initiation of DMBA-induced mammary cancer through the modulation of liver xenobiotic metabolism, formation of reactive metabolites and subsequent DNA damage in the target tissue.
Keywords
XMEsaryl-hydrocarbon receptorHCONQO1GSTsCYP1ethoxyresorufin-O-deethylaseAHRERODMUFADMBANrf27,12-dimethylbenz(a)anthraceneGC/MSXenobiotic metabolizing enzymesArachidonic acidPolyunsaturated fatty acidsPUFAmonounsaturated fatty acidsInducedOlive oilXenobiotic metabolismnuclear factor E2-related factor 2Polycyclic aromatic hydrocarbonsPAHsDietary lipidsgas chromatography/mass spectrometryLow-fatControlglutathione S-transferases
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Authors
Miguel Ángel Manzanares, Cristina de Miguel, M. Carme Ruiz de Villa, Regina M. Santella, Eduard Escrich, Montserrat Solanas,