Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5513794 | Microvascular Research | 2017 | 30 Pages |
Abstract
Nailfold capillaroscopy is one of the various noninvasive bioengineering methods used to investigate skin microcirculation. It is an effective examination for assessing microvascular changes in the peripheral circulation; hence it has a significant role for the diagnosis of Systemic sclerosis with the classic changes of giant capillaries as well as the decline in capillary density with capillary dropout. The decline in capillary density is one of microangiopathic features existing in connective tissue disease. It is detectable with nailfold capillaroscopy. This parameter is assessed by applying quantitative measurement. In this article, we reviewed a common method for calculating the capillary density and the relation between the number of capillaries as well as the existence of digital ulcers, pulmonary arterial hypertension, autoantibodies, scleroderma patterns and different scoring system.
Keywords
ACASSCCTDERSNFCDTDerythrocyte sedimentation NVCAECANailfold videocapillaroscopyRheumatoid arthritisAnticentromere antibodiesAntinuclear antibodiesAnti-endothelial cell antibodiessystemic sclerosisANAconnective tissue diseasesRaynaud phenomenondigital ulcerSystemic lupus erythematosusSLENailfold capillaroscopy
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Authors
Zahra Emrani, Abdolamir Karbalaie, Alimohammad Fatemi, Mahnaz Etehadtavakol, Björn-Erik Erlandsson,