Synthesis and anticancer activity of bile acid dendrimers with triazole as bridging unit through click chemistry

•Synthesis of new triazole based bile acid dendrimers via click chemistry.•All the dendrimers were characterized by spectral and analytical data.•All the dendrimers showed obvious cytotoxic activities against C6 glioma cells.•Higher-generation dendrimers exhibit better anticancer activity than lower-generation dendrimers.

Triazole-based novel dendrimers with bile acid surface groups have been synthesized through click chemistry by divergent approach and characterized by spectral data. All the dendrimers exhibit excellent anticancer activity. Higher-generation dendrimers exhibit better anticancer activity than the lower-generation dendrimers.

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