Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5522221 | Journal of Microbiological Methods | 2017 | 4 Pages |
Abstract
•Genotype 1 and 2 M. haemolytica have distinct mass spectrum profiles.•A MALDI-TOF MS assay was developed that identifies M. haemolytica genotypes 1 and 2.•The assay can be easily adapted into diagnostic labs using conventional MALDI-TOF MS.
Genotype 2 M. haemolytica predominantly associate over genotype 1 with the lungs of cattle with respiratory disease and ICEs containing antimicrobial resistance genes. Distinct protein masses were detected by MALDI-TOF MS between genotype 1 and 2 strains. MALDI-TOF MS could rapidly differentiate genotype 2 strains in veterinary diagnostic laboratories.
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