| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5522323 | Journal of Microbiological Methods | 2017 | 5 Pages |
Abstract
â¢The SLP assay detects bacterial peptidoglycan in biological fluids and tissues.â¢Generation of melanin by this assay is not reliable as a surrogate for bacteria.â¢Endogenous inflammation may activate the protease cascade leading to melanin.
The silkworm larvae plasma (SLP) assay has been developed as a means to detect bacterial peptidoglycan as a surrogate for live bacteria. Here, we present results that indicate that generation of melanin by this assay is not fully reliable as a surrogate marker for bacterial count.
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Authors
Michelle Ma, Tyler A. Rice, Caroline M. Percopo, Helene F. Rosenberg,