Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5522394 | Journal of Microbiological Methods | 2017 | 4 Pages |
Abstract
The lack of standardised protocols for the assessment of functional antibodies has hindered Streptococcus pyogenes research and the development of vaccines. A robust, high throughput opsonophagocytic bactericidal assay to determine protective antibodies in human and rabbit serum has been developed that utilises bioluminescence as a rapid read out.
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Authors
Natalie Lorenz, Jacelyn M.S. Loh, Nicole J. Moreland, Thomas Proft,