Article ID Journal Published Year Pages File Type
5534566 Molecular and Cellular Probes 2017 5 Pages PDF
Abstract

•Quantitative real-time multicolor multiplex PCR.•Rat strains differing in excitability of the nervous systems.•Gene copy number differences.

We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.

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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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