Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5546575 | Acta Pharmaceutica Sinica B | 2017 | 7 Pages |
Abstract
Finding new substrates with pharmaceutical potential for biocatalysts like P450 is always challenging. In this contribution, a P450 BM3 mutant 139-3 was observed to exhibit a hydroxylated activity toward androstenedione (1) at 1α-position.135
Keywords
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Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Xing Liu, Jian-qiang Kong,