| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5547559 | European Journal of Pharmaceutical Sciences | 2017 | 10 Pages |
Keywords
D2RPharmacometabolomicsrelative standard errorPK/PD modelingBrain extracellular fluid6-aminoquinolyl-N-hydroxysuccinimidyl carbamateRSEASCAAAADFWERDOPACN-methyl-d-aspartateNMDAUPLCVIPAQCRSDSRMPLS-DA3,4-dihydroxyphenylacetic acidl-3,4-dihydroxyphenylalaninel-DOPAPCAtris(2-carboxyethyl)phosphinearomatic amino acid decarboxylasebranched chain amino acidsrelative standard deviationvariable importance in projectionBCAAPartial least squares discriminant analysisPrincipal component analysisCNS drugsCNSTCEPcentral nervous systemMass spectrometryPharmacodynamicsSystems pharmacologyPharmacokineticsMethanolMeOHFamily wise error rateBiomarkersselective reaction monitoringhomovanillic acidHVAUltra High Performance Liquid Chromatographyquality controldopamine D2 receptor
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
W.J. van den Brink, J. Elassaiss-Schaap, B. Gonzalez-Amoros, A.C. Harms, P.H. van der Graaf, T. Hankemeier, E.C.M. de Lange,