Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case

Article ID	Journal	Published Year	Pages	File Type
5547835	European Journal of Pharmaceutical Sciences	2017	27 Pages	PDF

Keywords

Mrp2 OATP1B1 SMO Mrp3 UGT1A1 OATP1B3 UDP-glucuronosyltransferase 1A1 Organic anion transporting polypeptide 1B1 Bcrp organic anion transporting polypeptide 1B3 NADPH MCC AUC sequential minimal optimization Random forest Decision trees Classification SVM Support vector machines area under the curve Hyperbilirubinemia multidrug resistance-associated protein 2 multidrug resistance-associated protein 3 breast cancer resistance protein reduced nicotinamide adenine dinucleotide phosphate Liver

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case

Authors

Eleni Kotsampasakou, Sylvia E. Escher, Gerhard F. Ecker,