Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5550661 | International Journal of Pharmaceutics | 2017 | 8 Pages |
Abstract
Herein, we describe a simple spinneret setup for needleless coaxial electrospinning that exceeds the limited production capacity of current approaches. The proposed weir spinneret enables coaxial electrospinning from free liquid surface. This approach leads to the formation of coaxial nanofibers with higher and uniform shell/core ratio, which results in the possibility of better tuning of the degradation rate. The throughput and quality increase favor the broader application of coaxial nanofibers from weir spinnerets as systems for controlled drug delivery in regenerative medicine and tissue engineering.
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Lucie Vysloužilová, Matej Buzgo, Pavel Pokorný, JiÅà Chvojka, Andrea MÃÄková, Michala Rampichová, JiÅà Kula, Karel Pejchar, Martin BÃlek, David LukáÅ¡, Evžen Amler,