Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation

Article ID	Journal	Published Year	Pages	File Type
5550947	International Journal of Pharmaceutics	2016	13 Pages	PDF

Keywords

HFF CBA APC TLR SSC GM-CSF FSC PLL-g-PEG MFI CCR7 PLL MoDC LPS CCL21 PLGA Adjuvants cytometric bead array Immunostimulants interleukin tumor necrosis factor-α tetanus toxoid Toll-like receptor Dendritic cells Monocyte-derived dendritic cell antigen presenting cell TNF-α Vaccine formulation human foreskin fibroblast Fibroblasts lipopolysaccharide granulocyte macrophage colony-stimulating factor major histocompatibility complex MHC mean fluorescence intensity Microspheres Microsphere poly(I:C)poly(lactic-co-glycolic acid)Poly(l-lysine)Poly(ethylene glycol)PEG Polystyrene

Related Topics

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Surface-assembled poly(I:C) on PEGylated PLGA microspheres as vaccine adjuvant: APC activation and bystander cell stimulation

Authors

Annina M. Hafner, Blaise Corthésy, Marcus Textor, Hans P. Merkle,