Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5551601 | Saudi Pharmaceutical Journal | 2017 | 5 Pages |
Abstract
A series of ten novel chalcone incorporated quinazoline derivatives (11a-11j) were designed and synthesized. All the synthesized compounds were evaluated for their anticancer activities against four human cancer cell lines (A549, HT-29, MCF-7 and A375). Among them, four compounds, 11f, 11g, 11i and 11j showed more potent anticancer activity than the control drug, Combretastatin - A4.
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Authors
Sapavat Madhavi, Reddymasu Sreenivasulu, Jyothsna Pragathi Yazala, Rudraraju Ramesh Raju,