Article ID Journal Published Year Pages File Type
5554932 Fitoterapia 2017 7 Pages PDF
Abstract

Five new neo-clerodane diterpenoids, tiliifolins A-E (1-5), along with ten known ones, were isolated from the aerial part of Salvia tiliifolia. Their structures were proposed based on 1D and 2D NMR spectroscopic data analysis. All new compounds were evaluated for their neurotrophic activity on PC12 cells and cytotoxicity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW480), and compound 5 showed statistically significant neuroprotective effect in vitro assay.

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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