Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5554932 | Fitoterapia | 2017 | 7 Pages |
Abstract
Five new neo-clerodane diterpenoids, tiliifolins A-E (1-5), along with ten known ones, were isolated from the aerial part of Salvia tiliifolia. Their structures were proposed based on 1D and 2D NMR spectroscopic data analysis. All new compounds were evaluated for their neurotrophic activity on PC12 cells and cytotoxicity against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW480), and compound 5 showed statistically significant neuroprotective effect in vitro assay.
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Authors
Min Fan, Ying Bao, Zhi-Jun Zhang, Hong-Bin Zhang, Qin-Shi Zhao,