| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5554964 | Fitoterapia | 2017 | 6 Pages |
Abstract
Seven new cucurbitane triterpenoids, Pengxianencins A-G (1-7) including one alkaloid, were isolated from the ethanol extract of the tubers of Hemsleya penxianensis. Their structures were elucidated on the basis of extensive spectroscopic data, including 1D and 2D NMR spectra as well as HR-ESI-MS. The evaluation of inhibition activity against human Hela, MCF-7, and A-549 cell lines showed that compounds 1, 4, 6, 7 have different levels of cytotoxic activities, with IC50 values ranging from 1.67 to 45.28 μM.
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Authors
Pengfei Li, Nailiang Zhu, Meigeng Hu, Haifeng Wu, Tian Yu, Tongyu Wu, Dawei Zhang, Zhonghao Sun, Junshan Yang, Guoxu Ma, Xudong Xu,