Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5555078 | Fitoterapia | 2016 | 5 Pages |
Abstract
Two new steroidal glycosides (1-2) were isolated from the roots of Reineckia carnea, together with three known compounds (3-5). Their structures were determined on the basis of chemical methods and spectral data. Compounds 1-2 were the unique steroidal glycosides possessing structural feature of 14α-hydroxy-5β-steroids, and compounds 4-5 were isolated from R. carnea for the first time. The isolated compounds (1-5) were tested in vitro for their cytotoxic activities against the A549, HepG 2 and Caski cancer cell lines. Among them, the compounds 2 and 3 showed cytotoxicity against Caski cancer cell line with IC50 values of 34.4 and 3.7 μM, respectively.
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Authors
Ju-Yan Zheng, Qian Wang, Zhao-Xia L\iu, Cheng-Xiong Liu, Zhi-Yong Guo, Hong-Qi Zhang, Hai-Bo He, Xuan Tu, Kun Zou,