| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5555112 | Fitoterapia | 2017 | 7 Pages |
Abstract
Four new C21 steroidal glycosides (1-4), named perisepiumosides FI (1-4) together with six known steroidal glycosides (5-10) and four oligosaccharides (11-14), were isolated from the root bark of Periploca sepium. Their structures were characterized on the basis of 1D and 2D-NMR spectroscopic data as well as HR-ESI-MS analysis. The evaluation of inhibition activity against human A-549 and HepG2 cell lines indicated that compounds 2, 8, 10 and 13 showed different levels of cytotoxic activities with IC50 values ranging from 0.61 to 7.86 μM.
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Authors
Xin-Yue Gu, Zhou-Wei Wu, Lun Wang, Fu Li, Bin Chen, Kai Yu, Ming-Kui Wang,