| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5555139 | Fitoterapia | 2017 | 5 Pages |
Abstract
The fruits of Xanthium sibiricum Patr yielded five phenylpropanoid derivatives, named as xanthiumnolics A-E (1-5). Their structures were elucidated by spectroscopic analysis and comparison with literature data. The isolated ones were tested for their anti-inflammatory activities on lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7, and compound 5 showed strong inhibitory activities with IC50 value of 8.73 μM.
Graphical abstractDownload high-res image (355KB)Download full-size image
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Hai Jiang, Liu Yang, Guo-Xu Ma, Xu-Dong Xing, Mei-Ling Yan, Yan-Yan Zhang, Qiu-Hong Wang, Bing-You Yang, Hai-Xue Kuang, Xu-Dong Xu,