| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5555159 | Fitoterapia | 2017 | 7 Pages |
Abstract
Three new eudesmane sesquiterpenoids, commiphoranes E1-E3 (1-3), a new podocarpane diterpenoid, commiphorane F (4), three new triterpenoids, commiphoranes G1-G3 (5-7), and fourteen known terpenoids (8-21) were isolated from Resina Commiphora. The structures and relative configurations of new compounds were mainly assigned by spectroscopic methods. In particular, the absolute configuration of 3 was clarified by computational methods. Renoprotective effects of all these isolates were evaluated by using an ELISA assay in TGF-β1-induced rat kidney tubular epithelial cells. The present findings add new facets for chemical profiling of plant resins.
Graphical abstractDownload high-res image (220KB)Download full-size image
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Lu Dong, Qi Luo, Li-Zhi Cheng, Yong-Ming Yan, Yong-Xian Cheng, Shu-Mei Wang,