| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5556447 | Journal of Ethnopharmacology | 2017 | 8 Pages |
Abstract
Total sesquiterpene lactones from Inula helenium L. (TSL-IHL) could effectively inhibit the activation of NF-κB and MAPK pathways, suppress the inflammatory gene expressions in activated synovial fibroblasts and RAW 264.7 cells, and the oral treatment with TSL-IHL alleviated the paw swelling and arthritic severity in both AA and CIA rat arthritis models which indicated its therapeutic potential for rheumatoid arthritis.348
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Authors
Shuang Gao, Qun Wang, Xin-Hui Tian, Hui-Liang Li, Yun-Heng Shen, Xi-Ke Xu, Guo-Zhen Wu, Zhen-Lin Hu, Wei-Dong Zhang,