| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5556472 | Journal of Pharmacological and Toxicological Methods | 2017 | 14 Pages |
Abstract
The combined in vitro and in silico approach provides mechanistic insight regarding the potential for loperamide to generate cardiotoxicity in overdose situations. This strategy holds promise for improving cardiac safety assessment.
Keywords
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Jiansong Sheng, Phu N. Tran, Zhihua Li, Sara Dutta, Kelly Chang, Thomas Colatsky, Wendy W. Wu,