Circulating syndecan-1 predicts the development of disseminated intravascular coagulation in patients with sepsis

Article ID	Journal	Published Year	Pages	File Type
5583179	Journal of Critical Care	2018	34 Pages	PDF

Abstract

Syndecan-1 levels were associated with not only the severity of illness and mortality but also DIC development in sepsis, suggesting that syndecan-1 could be a predictive marker of DIC.

Keywords

PAI-1 FDP VCAM-1 ISTH SIRS APACHE II JAAM Syndecan-1 ROC Japanese association for acute medicine DIC AUC ICUs ROS antithrombin III Endothelial dysfunction DIC, Disseminated intravascular coagulation interleukin Enzyme-linked immunosorbent assay ELISA Systemic inflammatory response syndrome Acute Physiology and Chronic Health Evaluation II fibrin degradation products area under the curve plasminogen activator inhibitor 1 Vascular adhesion molecule-1 Predictive marker intensive care units SOFA Glycocalyx Reactive oxygen species receiver operating characteristic

Related Topics

Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine

Circulating syndecan-1 predicts the development of disseminated intravascular coagulation in patients with sepsis

Authors

Mitsunori MD, Hisatake MD, Hiroshi MD, Tomoya MD, Kentaro MD, Kouji PhD, Ikuro MD, Takeshi MD,