Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5599849 | Atherosclerosis Supplements | 2017 | 11 Pages |
Abstract
The expert working group placed great importance on an individualised approach in the management of FH and highlighted the unmet need for both improved education and communication with the laboratory for physicians when LDL-C levels are significantly elevated. Screening high-risk individuals, or cascade screening, is the most cost-effective way of identifying FH cases and initiating adequate statin therapy alone or in combination with other lipid-lowering therapies. In the case of severe FH, where plasma LDL-C levels remain high following maximum-tolerated statin and ezetimibe treatment, PCSK9 inhibitors should be considered.
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Authors
Michel Farnier, Fernando Civeira, Olivier Descamps,