Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5619543 | Progress in Cardiovascular Diseases | 2016 | 22 Pages |
Abstract
Blacks are especially susceptible to hypertension (HTN) and its associated organ damage leading to adverse cardiovascular, cerebrovascular and renal outcomes. Accordingly, HTN is particularly significant in contributing to the black-white racial differences in health outcomes in the US. As such, in order to address these health disparities, practical clinical practice guidelines (CPGs) on how to treat HTN, specifically in blacks, are needed. This review article is a timely addition to the literature because the most recent U.S. CPG more explicitly emphasizes race into the algorithmic management of HTN. However, recent clinical research cautions that use of race as a proxy to determine therapeutic response to pharmaceutical agents may be erroneous. This review will address the implications of the use of race in the hypertension CPGs. We will review the rationale behind the introduction of race into the U.S. CPG and the level of evidence that was available to justify this introduction. Finally, we will conclude with practical considerations in the treatment of HTN in blacks.
Keywords
CCBJNCHTNARBLVHCHDCPGsAfrican AmericansAngiotensin converting enzyme inhibitorsMinoritiescoronary heart diseasechronic kidney diseaseClinical practice guidelinesDiabetes mellitusblacksHypertensionhypertension or hypertensiveBlood pressurecardiovascularCalcium channel blockerAngiotensin receptor blockerACEI یا angiotensin convert enzyme inhibitorheart failureCKDLeft ventricular hypertrophyJoint National Committee
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Authors
Stephen K. Williams, Joseph Ravenell, Sara Seyedali, Husam Nayef, Gbenga Ogedegbe,