Síndrome de deleción 22q11: bases embriológicas y algoritmo diagnóstico

This article is a review of the embryologic basis for the congenital heart defects, epidemiology, genetics, pathophysiology and clinical aspects of this disease. This is a rare disease but is a potentially underdiagnosed cause of morbidity and mortality in Colombia, for which a strategy for its active search is also proposed and diagnostic aspects are discussed.