Article ID Journal Published Year Pages File Type
5630157 Journal of Neuroimmunology 2017 4 Pages PDF
Abstract

•We classified MG patients who underwent thymectomy into 3 groups based on pathology.•All patients of the 3 groups significantly improved throughout the course.•In MG PI status, patients with atrophic thymus after thymectomy were better than patients with TFH or thymoma.•We also found no differences in the comparison of mean dose of oral prednisolone.

To clarify the efficacy of thymectomy among myasthenia gravis (MG) patients with and without thymoma. We classified MG patients who underwent thymectomy into 3 groups, such as thymic atrophy group, thymic follicular hyperplasia (TFH) group and thymoma group. We compared the data of clinical features and postoperative prognosis at very short-term, short-term, and medium-term. The clinical course of MG patients with atrophic thymus after thymectomy was even better than those of TFH or thymoma, in this retrospective study. However, we found no significant differences in the comparison of mean dose of prednisolone between the 3 groups at each time point.

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