Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5630325 | Journal of Neuroimmunology | 2017 | 4 Pages |
â¢Patient presents with suspected bacterial meningomyelitisâ¢CSF and blood tests for bacteria, fungi, tuberculosis, antinuclear antibody all negativeâ¢MRI revealed several vertebral transverse and area postrema lesions.â¢Test for serum anti-aquaporin-4 antibody is positive.â¢Diagnosis may support hypothesis that pathogenesis of NMO triggered by infection.
A rare case of neuromyelitis optica spectrum disorder, suspected to be bacterial meningomyelitis as the initial manifestation, is reported. The patient presented with initial symptoms of meningomyelitis and fever. Cerebrospinal fluid analysis revealed pleocytosis (1280Â ÃÂ 106/L [98% lymphocytes]) and glucose level of 1.8Â mmol/L. Magnetic resonance imaging revealed >Â 3 vertebral, longitudinally extensive transverse myelitis and area postrema lesions. Right optic neuritis was experienced 20Â months after the first attack. Serum anti-aquaporin-4 antibody was positive, and a diagnosis of neuromyelitis optica spectrum disorder was made, supporting the hypothesis that the pathogenesis of neuromyelitis optica is triggered by infection.