Lesión cardiaca en paciente con sepsis pulmonar secundaria a E. coli productora de betalactamasa de espectro extendido

The systemic inflammatory response caused during the development of severe sepsis and septic shock triggers targets sites of specific action in certain cellular groups according to the type of cytokine, and the inoculum identified will generate the corresponding organ dysfunction. Examples of these are evident in the pulmonary pyroptosis induced by Pseudomonas aeruginosa1 and Escherichia coli involved cardiac dysfunction2. Preservation of the mitochondrial viability of these cell groups will determine the reversibility of these dysfunctions. Early diagnosis of this entity could have a favourable impact on quality, since currently the cardiomyopathy due to sepsis currently leads to high rates of morbidity and mortality, possibly due to the delay in the intervention.