| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5645938 | Dermatologica Sinica | 2016 | 4 Pages |
Abstract
In particular pemphigus cases, the phenotypic transition between pemphigus vulgaris and pemphigus foliaceus is observed with the change of antibody profile between anti-desmoglein (Dsg) 3 antibodies and anti-Dsg1 antibodies. In this study, we examined human leukocyte antigen (HLA) genotypes of four pemphigus patients who presented with the phenotypic transition and/or antibody profile shift. Two out of four patients possessed a DRB1*0405-DQB1*0401, and two out of four patients possessed a DRB1*1405-DQB1*0503. These alleles might be associated with the development of phenotypic transition and antibody profile shift.
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Authors
Seiko Mitsui, Koji Kamiya, Yoshiki Tokura, Keiji Iwatsuki, Yumi Aoyama,