Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5652876 | Injury | 2016 | 20 Pages |
Abstract
Hm-alginate demonstrates a greatly superior efficacy, relative to unmodified alginate and Kerlix⢠gauze dressings, in achieving hemostasis from a lethal femoral artery puncture in swine. This is a similar result as has been previously described when performing hydrophobic modification to chitosan. The current study further suggests that hydrophobic modification of a hydrophilic biopolymer backbone can significantly increase the hemostatic capabilities relative to the native biopolymer.
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Authors
Matthew B. Dowling, Apurva Chaturvedi, Ian C. MacIntire, Vishal Javvaji, John Gustin, Srinivasa R. Raghavan, Thomas M. Scalea, Mayur Narayan,