| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5671935 | Enfermedades Infecciosas y Microbiología Clínica | 2017 | 6 Pages |
Abstract
qnrB4 gene was the most prevalent PMQR gene detected, and was significantly associated with acquired AmpC β-lactamase DHA-1. PMQR determinants in association with other chromosomal-mediated quinolone resistance mechanisms, different to mutations in gyrA and parC (increased energy-dependent efflux, altered lipopolysaccharide or porin loss), could lead to ciprofloxacin MIC values that exceed breakpoints established by the main international committees to define clinical antimicrobial susceptibility breakpoints.
Keywords
Related Topics
Life Sciences
Immunology and Microbiology
Microbiology
Authors
Jesús Machuca, Jesús Agüero, Elisenda Miró, MarÃa del Carmen Conejo, Jesús Oteo, Germán Bou, Juan José González-López, Antonio Oliver, Ferran Navarro, Álvaro Pascual, Luis MartÃnez-MartÃnez,