Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5695518 | Gynecologic Oncology Reports | 2017 | 4 Pages |
Abstract
- Secondary, reversion mutations in BRCA genes can restore protein function.
- Reversion mutations can underlie resistance to therapies such as PARP inhibitors.
- Reversion mutations arise during the course of treatment.
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Authors
Paul Mayor, Laurie M. Gay, Shashikant Lele, Julia A. Elvin,