| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5807443 | Drug Metabolism and Pharmacokinetics | 2016 | 6 Pages |
Abstract
Metabolomics has been widely applied to toxicological fields, especially to elucidate the mechanism of action of toxicity. In this review, metabolomics application with focus on the studies of chronic and acute toxicities of drugs of abuse like stimulants, opioids and the recently-distributed designer drugs will be presented in addition to an outline of basic analytical techniques used in metabolomics. Limitation of metabolomics studies and future perspectives will be also provided.
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Authors
Kei Zaitsu, Yumi Hayashi, Maiko Kusano, Hitoshi Tsuchihashi, Akira Ishii,