Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5810116 | European Journal of Pharmaceutical Sciences | 2013 | 6 Pages |
Abstract
A series of nicotinic acid conjugates with non-steroidal anti-inflammatory drugs (NSAID's) have been effectively synthesized using TBTU in high yield and purity. All the synthesized conjugates were evaluated for their in vitro anti-inflammatory activity.
Graphical abstractWhere (a) Cs2CO3, 3-bromo 1-propanol, DMF; (b) nicotinic acid, TBTU, diisopropylamine, TMF.Download high-res image (106KB)Download full-size image
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Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Machhindra Gund, Fazlur-Rahman Nawaz Khan, Amit Khanna, Varadhan Krishnakumar,