Article ID Journal Published Year Pages File Type
5810116 European Journal of Pharmaceutical Sciences 2013 6 Pages PDF
Abstract

A series of nicotinic acid conjugates with non-steroidal anti-inflammatory drugs (NSAID's) have been effectively synthesized using TBTU in high yield and purity. All the synthesized conjugates were evaluated for their in vitro anti-inflammatory activity.

Graphical abstractWhere (a) Cs2CO3, 3-bromo 1-propanol, DMF; (b) nicotinic acid, TBTU, diisopropylamine, TMF.Download high-res image (106KB)Download full-size image

Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery
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