Development of a novel nanoparticle formulation of thymoquinone with a cold wet-milling system and its pharmacokinetic analysis

Article ID	Journal	Published Year	Pages	File Type
5817618	International Journal of Pharmaceutics	2016	7 Pages	PDF

Keywords

LDS NBT PXRD CWM HPC tmax PLM CoQ10 NaPB Cmax DSC p-Nitrosodimethylaniline ROS nitroblue tetrazolium VIs Ultraviolet Dissolution sodium phosphate buffer analysis of variance ANOVA Thymoquinone maximum concentration Rno time to maximum concentration Bioavailability Oral bioavailability SEM Scanning electron microscopy Polarized light microscopy Nanoparticle Visible light Hydroxypropyl cellulose Powder X-Ray Diffraction Differential scanning calorimetry HPLC high-performance liquid chromatography Positive control negative control Coenzyme Q10 Reactive oxygen species

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Development of a novel nanoparticle formulation of thymoquinone with a cold wet-milling system and its pharmacokinetic analysis

Authors

Takuya Nihei, Hiroki Suzuki, Asako Aoki, Kayo Yuminoki, Naofumi Hashimoto, Hideyuki Sato, Yoshiki Seto, Satomi Onoue,