Article ID Journal Published Year Pages File Type
5817742 International Journal of Pharmaceutics 2016 8 Pages PDF
Abstract
Dual functional nano-formulation can degrade in endosome due to low pH, released agmatine and siSAMDC can inhibit two critical pathways in polyamines biosynthesis respectively, inducing inhibition of tumor proliferation.
Keywords
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science
Preview
Polyamine metabolism-based dual functional gene delivery system to synergistically inhibit the proliferation of cancer
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