Dry powder inhaler formulation of high-payload antibiotic nanoparticle complex intended for bronchiectasis therapy: Spray drying versus spray freeze drying preparation

Article ID	Journal	Published Year	Pages	File Type
5818086	International Journal of Pharmaceutics	2016	30 Pages	PDF

Keywords

OD600 LEU DPI MIC DXT MMAD SFD PBS Chronic lung infection FPF Ultraviolet visible spectroscopy d-mannitol l-leucine MHb UV–Vis COPD Chronic obstructive pulmonary diseases Pulmonary drug delivery optical density at 600 nm Minimum inhibitory concentration Spray drying Spray freeze drying emitted dose PCs Dextran sulfate photon correlation spectroscopy Phosphate buffered saline Cystic fibrosis Aerodynamic diameter Mass median aerodynamic diameter SEM Man Mueller Hinton Broth scanning electron microscope PET Dry powder inhaler Fine particle fraction

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Dry powder inhaler formulation of high-payload antibiotic nanoparticle complex intended for bronchiectasis therapy: Spray drying versus spray freeze drying preparation

Authors

Hong Yu, Jeanette Teo, Jia Wei Chew, Kunn Hadinoto,