Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant

Article ID	Journal	Published Year	Pages	File Type
5819449	International Journal of Pharmaceutics	2014	17 Pages	PDF

Keywords

SISO QbD SNV APAP OPC SMCC MPA MGST ITAE FDA PID API RMSEP RMSE NIR MPC PLS RSD PCA Standard normal variate Magnesium stearate proportional integral relative standard deviation Principal component analysis Hybrid single input single output Process analytical technology partial least square root mean square error of prediction Pharmaceutical Root mean square error Food and Drug Administration Silicified microcrystalline cellulose Near infrared proportional integral derivative Active Pharmaceutical Ingredient principal component nanometer pat Continuous processing Model predictive control Quality by design

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science

Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant

Authors

Ravendra Singh, Abhishek Sahay, Krizia M. Karry, Fernando Muzzio, Marianthi Ierapetritou, Rohit Ramachandran,